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Main Instruments (Molecular Diagnostics)

Molecular Diagnostics Laboratory

Advanced Diagnostic Lab (IPPT)

USM

MAIN INSTRUMENT INSTRUMENT NAME PRINCIPLE

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S1000™ Thermal Cycler (BIO-RAD)

Thermal cyclers include Peltier effect technology for precise temperature control and thermal gradient to easily optimize PCR assays in a single run. Thermocycler use extends beyond simple PCR and the amplification of nucleic acids to include both random and site-directed mutagenesis as well as the in vitro construction of recombinant DNA sequences.

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MyCycler Thermal Cycler (BIO-RAD)

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Mastercycler Gradient (eppendorf)

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GenomeLab GeXP

Genetic Analysis System (BECKMAN COULTER)

 

Applications of this instrument include DNA sequencing and fragment analysis.

Assay principles - Capillary Electrophoretic (CE) Genetic Analysis System

 

 

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DNA Microarray Scanner (Agilent)

Applications of this instrument include Chromosomal Microarray (CMA) and Gene Express.

The microarray scanner is a sophisticated laser-induced fluorescence scanner designed to read microarrays printed on standard 1 in × 3 in slides.

The microarray scanner measures the fluorescence intensity of labeled sample nucleic acid (DNA and RNA) bound to microarrays. Its ability to measure fluorescence from two dyes simultaneously facilitates all two-color microarray studies. This technology provides for rapid, high-quality, automated scanning of microarrays.

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2100 Bioanalyzer (Agilent)

The Agilent 2100 Bioanalyzer system provides sizing, quantitation and quality control of DNA, RNA, proteins and cells on a single platform, providing high quality digital data.

Two assay principles - electrophoresis and flow cytometry

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